What is diazepam (valium)?
Diazepam oral tablet is a controlled substance drug that’s available as the brand-name drug Valium. before we know more about Diazepam we should know better what is diazepam .Diazepam also available as a generic drug. Generic drugs usually cost less. In some cases, they may not be available in every strength or form as the brand-name version.Diazepam is effective in the management of generalized anxiety disorder and panic disorder in appropriately selected patients. Its use prior to endoscopy or cardioversion relieves anxiety and diminishes the patient’s recall of the procedure. Preoperative use relieves anxiety and tension and may provide anterograde amnesia. Additional uses include the treatment of skeletal muscle spasms due to inflammation or trauma, spasticity (eg, multiple sclerosis, cerebral palsy, paraplegia, stiff-man syndrome), seizure disorders (eg, status epilepticus, febrile seizures), and alleviation of abstinence symptoms during alcohol withdrawal.
Diazepam is also available as an oral solution and a rectal gel.
Diazepam is an oral medication that is used to treat anxiety. It belongs to the benzodiazepine family of drugs
What brand names are available for Valium (diazepam)?
- Valium, Diastat Acudial, Diastat, and Diazepam Intensol are the brand names for diazepam available in the US.
- Dizac, Qpam, and Valrelease brand names have been discontinued in the US.
Why is Diazepam (valium) used ?
Diazepam oral tablet is used to treat the following conditions:
- symptoms caused by alcohol withdrawal, such as agitation or tremors
- add-on treatment for skeletal muscle spasms
- add-on treatment for certain types of seizures
It may be used as part of a combination therapy. That means you need to take it with other drugs.
Some important facts on Diazepam
- Diazepam oral tablet is available as both a generic and brand-name drug. Brand name: Valium.
- It is also available as an oral solution and a rectal gel.
- Diazepam is used to treat anxiety alcohol withdrawal, muscle spasms, and certain types of seizures.
- Sedation warning: This drug can slow down your brain’s activity and interfere with your judgment, thinking, and motor skills. You shouldn’t drink alcohol or use other drugs that can also slow down your brain’s activity while you’re on diazepam. You also shouldn’t drive, operate machinery, or do other tasks that require alertness until you know how this drug affects you.
- Increased seizures warning: If you are on diazepam as an add-on therapy for treating seizures, you may need a higher dose of your other seizure medications. This drug may cause more frequent and more severe seizures. If you suddenly stop taking diazepam, you may temporarily have more seizures.
How Does Diazepam work ?
Diazepam belongs to a class of drugs called benzodiazepines. A class of drugs refers to medications that work similarly. They have a similar chemical structure and are often used to treat similar conditions.
Diazepam increases the activity of gamma aminobutyric acid (GABA), a special chemical that can send signals throughout your nervous system. If you don’t have enough GABA, your body may be in an excited state and cause you to have anxiety, get muscle spasms, or have seizures. When you take this drug, you’ll have more GABA in your body. This will help decrease your anxiety, muscle spasms, and seizures.
Seizures can occur in more severe cases of withdrawal. Therefore, after extended use, diazepam should be slowly tapered under a doctor’s supervision rather than abruptly stopped.
What are the side effects of Diazepam(Valium)?
The most common side effects of diazepam are:
- Atlaxia (loss of balance)
Other important side effects include:
- Paradoxical reactions with excitability
- Lack of sleep
What is the dosage for Valium (diazepam)?
- Diazepam may be taken with or without food.
- Diazepam is disposed of by the Liver and excreted mainly by the kidney. Dosages of diazepam may need to be lowered in patients with abnormal kidney function.
- The usual oral diazepam dose for anxiety or seizures is 2-10 mg given 2-4 times daily.
- The usual rectal dose is 0.2-0.5 mg/kg and depends on the age of the patient.
Some additional Information on What is Diazepam?
Diazepam is a muscle relaxant and antianxiety drug. Peak blood levels are achieved within an hour after oral dose. Half-life in adults is 21 to 37 hours. The major metabolite (nordiazepam) has a half-life in adults of 50 to 99 hours. It is the major metabolite also of clorazepate and prazepam. Minor active metabolites of diazepam are temazepam (3-hydroxydiazepam) and oxazepam (3-hydroxy-N-diazepam). Diazepam may exhibit synergism with barbiturates, tricyclic antidepressants, and amine oxidase inhibitors. Toxicity may be additive with other central nervous system depressants, and ethanol enhances the absorption of diazepam itself. Many cases of overdose are seen but few fatalities result from use of this drug alone. A frequent finding is a combination of this drug and ethanol.
Diazepam side effects
Diazepam oral tablet can slow down your brain’s activity and interfere with your judgment, thinking, and motor skills. You shouldn’t drink alcohol or use other drugs that can also slow down your brain’s activity while you’re on Diazepam. You also shouldn’t drive, operate machinery, or do other tasks that require alertness until you know how this drug affects you. There are additional effects that you should also be aware of.
More common side effects
The more common side effects that occur with Diazepam include:
- tiredness or fatigue
- muscle weakness
- inability to control muscle movements (ataxia)
- dry mouth or excessive saliva
Serious side effects
- Worsening of seizures. Symptoms can include:
- increase in frequency
- increase in severity
- Changes in the brain or how you think. Symptoms can include:
- feelings of the room spinning (vertigo)
- slowed or slurred speech
- double or blurred vision
- thoughts of suicide
- memory loss
- Unexpected reactions. Symptoms can include:
- extreme excitement
- increased muscle spasms
- trouble sleeping
- Liver problems. Symptoms can include:
- yellowing of your skin or whites of your eyes (jaundice)
- Bladder problems. Symptoms can include:
- inability to urinate
- inability to hold urine
- Increase or decrease in sex drive.
- Withdrawal. Symptoms can include:
- abdominal or muscle cramps